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February 16, 2026MedicineOpen Access

Hemodialysis access type and RVDS link to moderate to high PH, affecting ~39% of patients.

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Why the study?

This study was conducted to use echocardiography to explore the prevalence of pulmonary hypertension in maintenance hemodialysis patients with different vascular accesses and analyze risk factors for combined pulmonary hypertension.

Does the type of vascular access affect the prevalence of pulmonary hypertension in maintenance hemodialysis patients?

Population

757 end-stage renal disease patients receiving maintenance hemodialysis

Comparison

Central vein catheter vs autogenous arteriovenous fistula/arteriovenous graft

Design

Cross-sectional analysis

Key result

39.23% of maintenance hemodialysis patients had moderate to high PH, with RVDS and left atrium diameter significantly linked to PH severity by access type.

Authors

JZJingwen Zhou

Discussion

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Member takes

Overview

PH common in hemodialysis and tied to access type; leaves open whether access modification alters PH risk.

Key Points

  • This research aims to identify the prevalence and risk factors of pulmonary hypertension in maintenance hemodialysis patients through echocardiographic assessment.
  • Conducted a cross-sectional analysis of 757 end-stage renal disease patients on maintenance hemodialysis.
  • Categorized patients based on type of vascular access: central vein catheter or arteriovenous access.
  • Used tricuspid regurgitation velocity to determine pulmonary hypertension prevalence.
  • Applied multinomial logistic regression to analyze risk factors.
  • 39.23% of patients exhibited moderate to high likelihood of pulmonary hypertension.
  • Significant risk factors for pulmonary hypertension included left atrium diameter and right ventricular end-systolic diameter.
  • Volume overload and vascular access type were linked to pulmonary hypertension incidence.
  • Caution is recommended for high-risk patients regarding the choice of vascular access.

Structured PICO

Does the type of vascular access affect the prevalence of pulmonary hypertension in maintenance hemodialysis patients?

P
Population
757 end-stage renal disease patients receiving maintenance hemodialysis
I
Intervention
Autogenous arteriovenous fistula (AVF)/arteriovenous graft (AVG)
C
Comparator
Central vein catheter (CVC)
O
Outcome
Prevalence of pulmonary hypertension (PH) and risk factors for combined PH based on echocardiographysurrogate

The prevalence of pulmonary hypertension in maintenance hemodialysis patients is high and closely related to vascular access type and right ventricular enlargement, suggesting careful evaluation of AVF/AVG in high-risk patients.

Cite This Study

Jingwen Zhou (2026) studied this question. 39.23% of maintenance hemodialysis patients had moderate to high PH, with RVDS and left atrium diameter significantly linked to PH severity by access type.

synapsesocial.com/papers/6992b4919b75e639e9b098e3https://doi.org/10.1097/md.0000000000043845
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prevalence and risk factors of echocardiographically suspected pulmonary hypertension in maintenance hemodialysis patients: a retrospective study2026
  2. 2A prospective echocardiographic evaluation of pulmonary hypertension in chronic hemodialysis patients in the United States: prevalence and clinical significance2010 · 106 citations
  3. 3Prevalence and Predictors of Pulmonary Hypertension in End-Stage Renal Disease: a Single-Center Cross-Sectional Study2026
  4. 4Doppler echocardiograph evaluation of pulmonary hypertension in patients undergoing hemodialysis2006 · 62 citations
  5. 5Frequency of Pulmonary Hypertension and Its Associated Risk Factors in End-Stage Renal Disease (ESRD) Patients on Maintenance Hemodialysis2024 · 1 citations