Key result
Pulmonary hypertension in hemodialysis patients with heart failure is linked to ~211% higher all-cause mortality.
Why the study?
Does pulmonary hypertension affect all-cause mortality and cardiovascular events in patients with heart failure on chronic hemodialysis?
Population
160 patients with a history of acute decompensated heart failure after maintenance hemodialysis therapy
Comparison
Presence of pulmonary hypertension vs Absence of pulmonary hypertension
Design
Cohort
Follow-up
until December 2013 or death
Authors
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PH in HD patients with HF remains understudied; leaves open questions on prevalence, risks, and outcomes.
Cohort (n=160)
Does pulmonary hypertension affect all-cause mortality and cardiovascular events in patients with heart failure on chronic hemodialysis?
Hazard Ratio: 3.11 (95% CI 1.53–6.31)
p-value: p=0.002
In patients with heart failure on chronic hemodialysis, pulmonary hypertension is strongly associated with mitral regurgitation and independently predicts increased all-cause mortality and cardiovascular events.
Hsieh et al. (2015) conducted a cohort in Chronic hemodialysis and heart failure (n=160). Pulmonary hypertension vs. No pulmonary hypertension was evaluated on All-cause mortality (HR 3.11, 95% CI 1.53-6.31, p=0.002). Pulmonary hypertension in patients on chronic hemodialysis and heart failure was independently associated with increased all-cause mortality (HR 3.11; 95% CI 1.53-6.31; P=0.002).
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