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February 17, 2026BMJ OpenOpen Access

Multicentre, retrospective observational study on risk factors of major cardiovascular adverse events in patients with chronic kidney disease in Taiwan

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Authors

CWChung‑Shun WongMWMei-Yi WuYCYi-Hsuan Roger Chen

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Overview

Retrospective cohort study assesses cardiovascular risks in chronic kidney disease patients, suggesting a need for better interventions.

Key Points

  • This study aims to evaluate the incidence and risk of major cardiovascular adverse events in patients with various stages of chronic kidney disease and end-stage kidney disease.
  • Conducted a retrospective cohort study across three hospitals in northern Taiwan.
  • Included 7038 adult patients with clinically confirmed CKD stages 3–5, excluding certain criteria.
  • Compared incidence of major adverse cardiovascular events between CKD and ESKD stages.
  • 49.8% of CKD patients and 64.1% of ESKD patients experienced major adverse cardiovascular events.
  • The ESKD group exhibited a higher risk of major adverse cardiovascular events (HR=1.52).
  • Adjusted hazard ratios indicate increasing risk with CKD progression, especially stage 5D (HR=2.32).

Cite This Study

Wong et al. (2026) studied this question.

synapsesocial.com/papers/6994055d4e9c9e835dfd6361https://doi.org/10.1136/bmjopen-2025-107969
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