This review highlights the distinctive clinical characteristics, treatment patterns, and outcomes of elderly heart failure patients, emphasizing the gaps in evidence due to their exclusion from major clinical trials.
Evidence gaps persist for elderly HF; leaves open optimal management pending inclusive trials.
The prevalence of heart failure (HF) increases with age. While clinical trials suggest that contemporary evidence-based HF therapies have reduced morbidity and mortality, these trials largely excluded the elderly. Questions remain regarding the clinical characteristics of elderly HF patients and the impact of contemporary therapies on their outcomes. This review presents the epidemiology of HF in the elderly and summarizes the data on the pathophysiology of the ageing heart. The clinical characteristics, treatment patterns, and outcomes of elderly HF patients are explored. Finally, the main gaps regarding HF therapies in the elderly and the opportunities for future trials are highlighted.
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Lazzarini et al. (2013) studied this question.
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