What question did this study set out to answer?

This research aims to understand how often children are retested for tissue transglutaminase antibodies after an initial positive result for celiac disease.

February 19, 2026Journal of the Canadian Association of GastroenterologyOpen Access

Frequency of follow-up testing for tissue transglutaminase antibodies after initial positivity among children: An analysis of real-world data from a population-based cohort in Canada

View Full Paper

Ask AI

Bookmark

Authors

JKJames A. KingAlberta Health Services JHJessalyn K. HolodinskyUniversity of Calgary AMAmy MetcalfeUniversity of Calgary

Discussion

Member takes

Implication

Analysis reveals follow-up testing variation for celiac disease in children, suggesting implications for monitoring practices.

Key Points

This research aims to understand how often children are retested for tissue transglutaminase antibodies after an initial positive result for celiac disease.
Utilized administrative data from Alberta, Canada, from 2016 to 2023.
Identified children with first positive tTG-IgA results and stratified them by baseline result levels.
Estimated mean cumulative functions to analyze repeated tTG-IgA tests across time.
49.1% of children had high baseline tTG-IgA values at initial positivity.
Children with baseline tTG-IgA ≥10× ULN had an average of 3.7 overall follow-up tests over 5 years.
Significant differences in follow-up testing noted based on urban-rural status and socioeconomic gradient.

Cite This Study

King et al. (2026) studied this question.

synapsesocial.com/papers/6996a8a9ecb39a600b3ef8c5 https://doi.org/10.1093/jcag/gwag005

View Full Paper

Ask AI

Bookmark

Frequency of follow-up testing for tissue transglutaminase antibodies after initial positivity among children: An analysis of real-world data from a population-based cohort in Canada

Discussion

Member takes

Implication

Key Points

Cite This Study

Frequency of follow-up testing for tissue transglutaminase antibodies after initial positivity among children: An analysis of real-world data from a population-based cohort in Canada

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider