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The review aims to assess silk fibroin's properties and biocompatibility for medical applications.

Silk Fibroin in Medicine: A Review on ISO10993 Biocompatibility, Preclinical Evidence, and Clinical Perspectives

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The review aims to assess silk fibroin's properties and biocompatibility for medical applications.
Comprehensive literature review of silk fibroin properties and biomedical applications
Evaluation of ISO 10993 biocompatibility data
Summary of preclinical findings in various tissue models
Analysis of clinical trial outcomes for silk fibroin-based materials
Silk fibroin demonstrates low toxicity and good blood compatibility
Mild inflammatory responses were observed with silk fibroin materials
Successful tissue repair was noted in skin, bone, and nerve models
Clinical trials report effective tissue reconstruction using silk fibroin

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This review explores silk fibroin's biocompatibility and effectiveness in tissue repair, suggesting strong clinical potential.

Jitpibull et al. (2026) studied this question.

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