Why the study?
Does the method of revascularization (PCI vs CABG) affect LVEF improvement in patients with HFrEF and coronary heart disease?
Does the method of revascularization (PCI vs CABG) affect LVEF improvement in patients with HFrEF and coronary heart disease?
In patients with HFrEF and coronary heart disease, the method of revascularization does not significantly affect the degree of LVEF improvement, but specific baseline clinical factors predict marked recovery.
Suggests baseline myocardial reserve rather than revascularization modality drives functional recovery in ischemic cardiomyopathy; leaves open.
The method of revascularization (PCI vs CABG) had no effect on LVEF improvement. Patients with severely impaired baseline LVEFs, triple-vessel disease, or no history of MI tended to exhibit marked LVEF improvement (≥10%) after revascularization. In addition, LVESD, LVEDD, hyperuricemia, clopidogrel use and loop diuretic affected the degree of improvement.
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Peng et al. (2018) studied this question.
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