Low ascending aortic [18F]-sodium fluoride uptake predicted most rapid aortic growth, while high uptake indicated a stiffer, slow-growing aortic phenotype in bicuspid aortic valve patients.
Does [18F]-sodium fluoride PET imaging predict aortic growth and stiffness in patients with a bicuspid aortic valve?
[18F]-sodium fluoride PET imaging is a promising noninvasive approach to identify microcalcified disease phenotypes and predict aortic growth in bicuspid aortic valve aortopathy.
Absolute Event Rate: 0% vs 0%
In this cohort study of patients with a bicuspid aortic valve, the most rapid aortic growth was seen in those with low 18F-sodium fluoride ascending aortic uptake, indicating reduced aortic wall integrity. High ascending aortic 18F-sodium fluoride uptake was associated with a stiffer and slow-growing ascending aortic phenotype. These findings suggest that 18F-sodium fluoride PET imaging represents a promising new noninvasive approach to identify a microcalcified disease phenotype in thoracic aortopathy among patients with a bicuspid aortic valve.
Nash et al. (Mon,) reported a other. Low ascending aortic [18F]-sodium fluoride uptake predicted most rapid aortic growth, while high uptake indicated a stiffer, slow-growing aortic phenotype in bicuspid aortic valve patients.