What question did this study set out to answer?

To investigate the utility of 18F FET PET imaging in diagnosing and monitoring circumscribed astrocytic gliomas.

February 26, 2026Open Access

Clinical potential of 18FFET PET in patients with circumscribed astrocytic glioma

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Authors

JWJan-Michael Werner MMMaximilian J. MairLMU Klinikum MWMichael M. Wollring

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Implication

This retrospective analysis evaluates 18F FET PET imaging to assess tumor characteristics in adult circumscribed astrocytic glioma, suggesting a role in clinical management.

Key Points

To investigate the utility of 18F FET PET imaging in diagnosing and monitoring circumscribed astrocytic gliomas.
Retrospective analysis of adult CAG patients undergoing 18F FET PET imaging at three institutions.
Assessment of tumor-to-brain ratios (TBRmax, TBRmean) and metabolic tumor volumes using PET RANO 1.0 criteria.
ROC analysis and Fisher’s exact test to evaluate diagnostic performance.
79 18F FET PET scans were performed on 42 patients.
65% of WHO grade 1 and 100% of grades 2 and 3 CAG showed measurable 18F FET uptake.
Accuracy in identifying treatment-related changes was 82% with single PET scans and 100% with serial scans.

Cite This Study

Werner et al. (2026) studied this question.

synapsesocial.com/papers/699fe36b95ddcd3a253e751a https://doi.org/10.34734/fzj-2025-04995

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Implication

This retrospective analysis evaluates 18F FET PET imaging to assess tumor characteristics in adult circumscribed astrocytic glioma, suggesting a role in clinical management.

Clinical potential of 18FFET PET in patients with circumscribed astrocytic glioma

Discussion

Member takes

Implication

Key Points

Cite This Study

Clinical potential of 18FFET PET in patients with circumscribed astrocytic glioma

Discussion

Member takes

Implication

Key Points

Cite This Study

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