What does this research mean for the field?

The combination of multi-spectral optoacoustic tomography (MSOT) and diffuse reflectance spectroscopy (DRS) provides a noninvasive method to accurately assess the composition of skin and subcutaneous tissues, including water, lipids, and collagen. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.ESTABLISHES_NEW_DIRECTION.

What question did this study set out to answer?

The aim is to evaluate the effectiveness of merging MSOT and DRS for assessing skin and muscle composition in vivo.

February 27, 2026Open Access

Water, Collagen, and Lipid Content in the Human Skin and Muscles Assessed with Near‐Infrared Diffuse Reflectance Spectroscopy and Multi‐Spectral Optoacoustic Tomography

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Authors

DDDenis А. DavydovSechenov University AKAlexey A. Kurnikov PSPavel SubochevRadiophysical Research Institute

Discussion

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Implication

Demonstrates the combined use of MSOT and DRS to enhance body composition analysis in diverse populations, suggesting improved diagnostic potential.

Key Points

The aim is to evaluate the effectiveness of merging MSOT and DRS for assessing skin and muscle composition in vivo.
Introduced a strategy that combines multi-spectral optoacoustic tomography and diffuse reflectance spectroscopy.
Measured distinct absorption peaks for water, lipids, and collagen in human skin and muscles.
Utilized bioimpedance analysis to correlate collagen magnitude with muscle mass.
Lipid absorption is significantly higher than that of collagen in skin tissues.
The DRS method detects collagen signals effectively in individuals with thinner hypodermis.
MSOT demonstrates superior capability in visualizing and quantifying tissue composition compared to DRS alone.

Cite This Study

Davydov et al. (2025) studied this question.

synapsesocial.com/papers/69a13591ed1d949a99abf8d7 https://doi.org/10.5167/uzh-292515

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February 27, 2026Open Access

Water, Collagen, and Lipid Content in the Human Skin and Muscles Assessed with Near‐Infrared Diffuse Reflectance Spectroscopy and Multi‐Spectral Optoacoustic Tomography

View Full Paper

Ask AI

Bookmark

Authors

DDDenis А. DavydovSechenov University AKAlexey A. Kurnikov PSPavel SubochevRadiophysical Research Institute

Discussion

Member takes

Implication

Demonstrates the combined use of MSOT and DRS to enhance body composition analysis in diverse populations, suggesting improved diagnostic potential.

Key Points

The aim is to evaluate the effectiveness of merging MSOT and DRS for assessing skin and muscle composition in vivo.
Introduced a strategy that combines multi-spectral optoacoustic tomography and diffuse reflectance spectroscopy.
Measured distinct absorption peaks for water, lipids, and collagen in human skin and muscles.
Utilized bioimpedance analysis to correlate collagen magnitude with muscle mass.
Lipid absorption is significantly higher than that of collagen in skin tissues.
The DRS method detects collagen signals effectively in individuals with thinner hypodermis.
MSOT demonstrates superior capability in visualizing and quantifying tissue composition compared to DRS alone.

Cite This Study

Davydov et al. (2025) studied this question.

synapsesocial.com/papers/69a13591ed1d949a99abf8d7 https://doi.org/10.5167/uzh-292515

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