What question did this study set out to answer?

This review aims to elucidate the systemic changes in immune function due to aging and their implications for health.

February 28, 2026CellsOpen Access

Network Rewiring in the Aging Immune System: From Chronic Inflammation to Age-Related Pathologies

View Full Paper

Ask AI

Bookmark

Authors

This review demonstrates the mechanisms linking chronic inflammation to age-related diseases, suggesting targeted therapies for improved immunity.

This review aims to elucidate the systemic changes in immune function due to aging and their implications for health.
Summarized recent advances in immune dysfunction mechanisms in aging.
Analyzed the interplay between chronic inflammation and failed tissue repair.
Reviewed impacts on both innate and adaptive immunity and their roles in age-related diseases.
Highlighted emerging therapeutic strategies for restoring immune balance.
Aging leads to impaired resolution of inflammation and ongoing tissue damage.
Chronic inflammation reinforces age-related diseases, like cancer and neurodegenerative disorders.
Emerging therapies may offer potential for modulating immune aging and enhancing healthspan.

Müller et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark

This review demonstrates the mechanisms linking chronic inflammation to age-related diseases, suggesting targeted therapies for improved immunity.