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November 20, 2001Circulation

Impact of Atrial Fibrillation on the Clinical Course of Hypertrophic Cardiomyopathy

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Why the study?

Does atrial fibrillation increase the risk of heart failure-related mortality, stroke, and severe functional disability in a community-based hypertrophic cardiomyopathy population?

Population

Community-based hypertrophic cardiomyopathy (HCM) population

Design

Cohort

Follow-up

9 years

Authors

Iacopo OlivottoIacopo OlivottoHeart Failure / CardiomyopathyFCFranco CecchiUniversity of PisaSCSusan A. CaseyHeart Failure / Cardiomyopathy

Discussion

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Implication

AF complications in HCM may warrant vigilance; observational data leave open whether intervention improves outcomes.

Structured PICO

Does atrial fibrillation increase the risk of heart failure-related mortality, stroke, and severe functional disability in a community-based hypertrophic cardiomyopathy population?

P
Population
Community-based hypertrophic cardiomyopathy (HCM) population
I
Intervention
Atrial fibrillation (AF) exposure
O
Outcome
Heart failure-related mortality, stroke, and severe functional disabilityhard clinical

In patients with hypertrophic cardiomyopathy, atrial fibrillation is a common complication that significantly increases the risk of mortality, stroke, and functional decline, particularly in younger patients or those with outflow obstruction.

Cite This Study

Olivotto et al. (2001) studied this question.

synapsesocial.com/papers/69a49ddb2c251382ac68c8dfhttps://doi.org/10.1161/hc4601.097997

Topics

Atrial fibrillationHypertrophic cardiomyopathyPersistent AF managementAF ablation outcomesAnticoagulation in AF
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epidemiologic Features of Chronic Atrial Fibrillation1982 · 2,340 citations
  2. 2Arrhythmia in hypertrophic cardiomyopathy. I: Influence on prognosis.1981 · 424 citations
  3. 3Risk for atrial fibrillation in patients with hypertrophic cardiomyopathy assessed by signal averaged P wave duration.1997 · 66 citations
  4. 4Clinical Course of Hypertrophic Cardiomyopathy in a Regional United States Cohort1999 · 556 citations
  5. 5Epidemiology of Hypertrophic Cardiomyopathy–Related Death2000 · 804 citations