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Clinical performance of an IGF1 assay improves hormone assessment in endocrinology, suggesting a reliable reference approach.
Our LC-MS/MS IGF1 assay integrated with its own population-based normative dataset demonstrated superior alignment with clinical assessment compared with LBA results. In our setting, this method provides a clinically reliable benchmark for IGF1 interpretation and may serve as a reference for IGF1 harmonization and broader adoption of the Lifelines normative dataset in routine endocrinology.
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Vos et al. (2026) studied this question.
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