What question did this study set out to answer?

This review aims to explore the relationship between anesthetic agents, postoperative pain intensity, and postoperative delirium risk.

March 3, 2026Open Access

The Influence of Pharmacological Agents Used During General Anesthesia on the Intensity of Postoperative Pain and the Occurrence of Post-Anesthetic Delirium—A Scoping Review

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A scoping review examines how anesthesia medications affect pain and delirium in surgical patients, suggesting implications for treatment.

This review aims to explore the relationship between anesthetic agents, postoperative pain intensity, and postoperative delirium risk.
Conducted a scoping review from December 2024 to December 2025
Reviewed articles published between 2015 and 2025
Evaluated trials focusing on various anesthetic agents and patient populations
Dexmedetomidine and remimazolam were linked to reduced postoperative delirium incidence
Higher doses of dexmedetomidine improved pain control without delaying recovery
Hydromorphone showed better pain control compared to sufentanil
Magnesium sulfate alleviated postoperative symptoms such as pain
Ketamine's effectiveness in delirium prevention was inconsistent

Dąbrowska et al. (2026) studied this question.

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A scoping review examines how anesthesia medications affect pain and delirium in surgical patients, suggesting implications for treatment.