Research demonstrates accurate characterization of sickle cell disorders using diagnostic tests, suggesting improved diagnosis and management.
Most SCDs encountered in a hospital-setting are reliably characterized by HPLC and hemogram data, supplemented with the sickling test and, where necessary, parental HPLCs. Molecular analysis aids in accurate characterization of complex cases and in resolution of diagnostic discrepancies; however, their own pitfalls must be borne in mind.
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Yadav et al. (2026) studied this question.
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