What question did this study set out to answer?

The aim is to evaluate the justification and clinical evidence for using sodium bicarbonate to correct metabolic acidosis.

March 4, 2026Journal of Intensive CareOpen Access

Sodium bicarbonate for “metabolic acidosis”: an illustration of the Goodhart’s law

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Authors

SDSylvain DiopAR2i MAMaxime AparicioHôpital Européen Georges-Pompidou RMRoman MounierSorbonne Université

Discussion

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Implication

This commentary highlights concerns regarding sodium bicarbonate's effectiveness in correcting metabolic acidosis, suggesting potential risks in critical care settings.

Key Points

The aim is to evaluate the justification and clinical evidence for using sodium bicarbonate to correct metabolic acidosis.
Discussion of physiological rationale behind sodium bicarbonate use
Examination of intracellular vs extracellular pH effects
Review of evidence regarding sodium bicarbonate infusion and osmolarity impact
Sodium bicarbonate correction has minimal impact on intracellular pH.
Transitory blood pH changes do not translate into significant clinical benefits.
Potential risks include altered patient osmolarity and cell function effects.

Cite This Study

Diop et al. (2026) studied this question.

synapsesocial.com/papers/69a7cd8cd48f933b5eeda049 https://doi.org/10.1186/s40560-026-00870-x

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Implication

This commentary highlights concerns regarding sodium bicarbonate's effectiveness in correcting metabolic acidosis, suggesting potential risks in critical care settings.

Sodium bicarbonate for “metabolic acidosis”: an illustration of the Goodhart’s law

Discussion

Member takes

Implication

Key Points

Cite This Study

Sodium bicarbonate for “metabolic acidosis”: an illustration of the Goodhart’s law

Discussion

Member takes

Implication

Key Points

Cite This Study

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