Copper-Catalysed Decarboxylative Alkynylation-Cyclization Reaction of Propargylic Cyclic Carbonates with Nitrile Imines to Access Tetrasubstituted Pyrazoles

Key Points

• The aim is to develop a regioselective synthesis method for tetrasubstituted pyrazoles.
• Utilized copper-catalyzed reactions
• Combined propargylic cyclic carbonates with nitrile imines
• Employed decarboxylative alkynylation-cyclization approach
• Successfully synthesized tetrasubstituted pyrazoles
• Demonstrated regioselectivity in the formation of products
• Reactions showed high yields and efficiency