Prospective analysis reveals that anti-spike IgG avidity boosts neutralization in primary infections and immunizations, suggesting wider applications.
Comprehensive serological profiles of early SARS-CoV-2 primary infections and immunizations provided a model showing that the antiviral neutralization potency is enhanced by anti-spike IgG avidity. The methodology presented is applicable widely beyond COVID-19.
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Nurmi et al. (2026) studied this question.
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