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March 8, 2026

Multi-center development and validation of a standardized protocol for biotinylated red blood cell analysis.

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Authors

SMSusanne MarschnerVitalantDLDeborah LeeHome OfficeNRNeeta RuggUniversity of Cincinnati

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Implication

Multi-center validation demonstrates reliable labeling in biotinylated red blood cells, indicating potential for consistent results across different locations.

Key Points

  • The research aims to develop and validate a standardized protocol for analyzing biotinylated red blood cells.
  • Developed the BioRBC protocol across multiple centers.
  • Assessed reliability and reproducibility of labeling.
  • Planned in vivo performance studies comparing BioRBCs with dual radiolabeling.
  • Achieved minimal inter-site variability in labeling.
  • Confirmed reliability of the BioRBC protocol for future studies.

Cite This Study

Marschner et al. (2026) studied this question.

synapsesocial.com/papers/69ada892bc08abd80d5bbb42https://doi.org/10.1111/trf.70157
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