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March 10, 2026AnemiaOpen Access

Strengthening Newborn Screening: A Pilot Health Program Management for Sickle Cell Disease in Côte d’Ivoire

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Authors

KKKouassi Gustave KoffiRDRomuald Sery DasseCentre Hospitalier Universitaire de CocodySBSara Akou Bognini

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Implication

A pilot program implements newborn screening for sickle cell disease in Côte d’Ivoire, highlighting necessary healthcare improvements.

Key Points

  • This pilot program aims to evaluate newborn screening for sickle cell disease and assess the birth prevalence and linkage to care in Côte d’Ivoire.
  • Conducted a prospective, multicenter cross-sectional study from June 2022 to December 2024.
  • Screened umbilical cord blood samples of newborns using rapid diagnostic tests (RDT).
  • Confirmed positive RDT results with capillary electrophoresis.
  • Screened 6,337 newborns, with 825 (13.02%) having abnormal hemoglobin profiles.
  • 112 infants diagnosed with sickle cell disease confirmed through capillary electrophoresis.
  • Only 68 of the diagnosed infants were enrolled in comprehensive care services.

Cite This Study

Koffi et al. (2026) studied this question.

synapsesocial.com/papers/69af958570916d39fea4d367https://doi.org/10.1155/anem/4758882
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Neonatal screening for sickle cell anaemia in the Democratic Republic of the Congo: experience from a pioneer project on 31 204 newborns2008 · 200 citations
  2. 2Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates2012 · 1,212 citations
  3. 3Clinical outcomes in children with sickle cell disease living in England: a neonatal cohort in East London2007 · 359 citations
  4. 4Neonatal screening for sickle cell disorders in Ouagadougou, Burkina Faso: a pilot study2005 · 44 citations
  5. 5Pathogenesis and Treatment of Sickle Cell Disease1997 · 1,169 citations