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September 30, 2025British Journal of HaematologyOpen Access

Systematic point‐of‐care newborn screening for sickle cell disease in rural Mali, West Africa

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Authors

AGAldiouma GuindoKCKory CablayJKJoseph Kamate

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Overview

This evaluation shows a successful newborn screening program in rural Mali, indicating effective coverage and SCD detection.

Key Points

  • 99.2% of newborns were screened for sickle cell disease using point-of-care testing methods.
  • A total of 118 haemoglobin SS cases were identified, indicating a prevalence rate of 1.34%.
  • The study evaluated the feasibility of point-of-care screening in a high-volume rural hospital setting.
  • This model may provide a framework for expanding newborn screening to other rural regions in sub-Saharan Africa.

Cite This Study

Guindo et al. (2025) studied this question.

synapsesocial.com/papers/68dc261d8a7d58c25ebb2b36https://doi.org/10.1111/bjh.70158
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Point-of-Care Newborn Screening for Sickle Cell Disease at Selected Health Facilities in the Gambia2024 · 8 citations
  2. 2Strengthening Newborn Screening: A Pilot Health Program Management for Sickle Cell Disease in Côte d’Ivoire2026
  3. 3Determination of birth prevalence of sickle cell disease using point of care test HemotypeSC™ at Rundu Hospital, Namibia2024 · 9 citations
  4. 4The Key to Combating Sickle Cell Disease in High-Prevalence Regions Like Mali: Hemoglobin Electrophoresis for All, From Birth to Marriage2025
  5. 5Integration of newborn screening for sickle cell disease into primary health care in Bukavu, Democratic Republic of the Congo: a pilot study2025 · 6 citations