Why the study?
Does COX2 inhibition reduce aortic valve calcification in preclinical models of CAVD?
Population
In vitro and in vivo models of calcific aortic valve disease (CAVD)
Design
Preclinical
Authors
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COX2 inhibition reduces aortic valve calcification in animal models; hypothesis-generating for calcific aortic valve disease therapy, pending clinical trials.
Does COX2 inhibition reduce aortic valve calcification in preclinical models of CAVD?
COX2 inhibition reduces aortic valve calcification in preclinical models, suggesting a potential therapeutic target for calcific aortic valve disease.
Wirrig et al. (2015) studied this question.
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