While right atrial pressure (RAP) reflects disease severity and carries prognostic value in patients with severe tricuspid regurgitation (TR), its noninvasive estimation remains limited in accuracy. The aim of this study is to evaluate the ability of cardiac magnetic resonance imaging (CMR) to estimate RAP by identifying relevant imaging parameters in patients with severe TR. Between September 2021 and January 2026, 47 consecutive patients who underwent cardiac catheterization and CMR for severe TR were enrolled from a tertiary center. In addition to conventional parameters, right ventricular (RV) and right atrial (RA) strain were measured from apical four-chamber images of CMR. Pressure profiles including the mean RAP were obtained via cardiac catheterization. The median age was 69 years, and secondary TR was the predominant etiology (83.0%). The mean RAP was 10.0 mmHg, and the median interval between catheterization and CMR was 1 day. Among volumetric parameters, indexed RV end-diastolic volume (RVEDVi; r=0.58, p10 mmHg was 0.78 for RVEDVi and 0.82 for RA longitudinal strain. RVEDVi and RA longitudinal strain were significantly associated with invasively measured RAP in patients with severe TR. These findings suggest that CMR has potential as a noninvasive tool for estimating RAP in this population. Noninvasive estimation of RA pressure using cardiac magnetic resonance in severe tricuspid regurgitation CMR, cardiac magnetic resonance imaging; RA, right atrial; RAP, right atrial pressure; RVEDV; right ventricular end-diastolic volume; TR, tricuspid regurgitation; TTE, transthoracic echocardiography.
Kim et al. (Sun,) studied this question.