What question did this study set out to answer?

This review aims to identify and analyze risk factors contributing to infections in patients with multiple myeloma.

Risk factors for infections in patients with multiple myeloma: a systematic review and meta-analysis

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Systematic review identifies risk factors for infections in multiple myeloma patients, suggesting clinical interventions.

This review aims to identify and analyze risk factors contributing to infections in patients with multiple myeloma.
Conducted a systematic review and meta-analysis of observational studies from various databases.
Included studies assessed risk factors for infection in multiple myeloma patients up to July 2025.
Used the NOS tool to assess literature quality and performed meta-analysis with Stata 15.0.
Age > 65 years associated with 1.72x increased infection risk.
Male gender shown to increase infection risk by 1.70x.
Smoking significantly elevates infection risk (OR = 2.97).
International Staging System III linked to a 2.22x infection risk.
Use of immunomodulatory drugs raises infection risk by 3.40x.

He et al. (2026) studied this question.

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