Key result
CardioCel tricuspidation for asymmetric bicuspid aortic valves yields 100% short-term survival and minimal insufficiency.
Why the study?
Does tricuspidation using bovine pericardium neo-cusps improve hemodynamics and valve competence in patients with asymmetric bicuspid aortic valves?
Observational (n=15)
Does tricuspidation using bovine pericardium neo-cusps improve hemodynamics and valve competence in patients with asymmetric bicuspid aortic valves?
A novel tricuspidation technique using bovine pericardium for asymmetric bicuspid aortic valves provides excellent short-to-mid-term hemodynamic results and avoids the need for concomitant aortic root downsizing.
May support tricuspidation with neo-cusps for asymmetric BAV repair; hypothesis-generating and requires prospective validation.
We present a novel technique for tricuspidation of the very asymmetrical bicuspid aortic valve (AV) with commissural orientation of about 120-140, via replacement of the fused aortic valve cusp with two neo-cusps. The neo-cusps are fashioned from bovine pericardium and sutured to the annulus. Successful repair using the described technique requires good quality and adequate commissure height of the non-fused cusp. Since 2020, this technique has been applied in 15 patients. To date, all patients are alive with well-functioning AVs, presenting no or trivial insufficiency, large orifice areas, and nearly physiological transvalvular gradients.
No takes yet. Share an insight, caveat, or question.
Urbanski et al. (2026) conducted an observational in Asymmetric bicuspid aortic valve (n=15). Tricuspidation using CardioCel bovine pericardium neo-cusps was evaluated on Survival and valve function (insufficiency and gradients). Tricuspidation of asymmetric bicuspid aortic valves using CardioCel neo-cusps resulted in 100% survival and well-functioning valves with no or trivial insufficiency in 15 patients over short- to mid-term follow-up.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: