What question did this study set out to answer?

This research aims to evaluate the impact of bronchiectasis on outcomes in patients with advanced lung cancer undergoing chemotherapy.

March 21, 2026ESMO OpenOpen Access

188eP Skeletal muscle, subcutaneous and intramuscular fat as prognostic biomarkers in TKI-treated fusion-positive NSCLC

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Authors

MSMarco Sposito LPLuca PasqualinUniversity of Verona ABA. BonatoUniversity of Verona

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Implication

Retrospective cohort study finds bronchiectasis does not significantly affect survival in advanced lung cancer patients undergoing chemotherapy, suggesting further investigation is needed.

Key Points

This research aims to evaluate the impact of bronchiectasis on outcomes in patients with advanced lung cancer undergoing chemotherapy.
Conducted a retrospective cohort study of stage III-IV lung cancer patients receiving systemic chemotherapy.
Classified patients by the presence of radiologically confirmed bronchiectasis.
Measured outcomes included respiratory morbidity and overall survival using Kaplan-Meier method.
Included 228 patients; 13 had bronchiectasis and 215 did not.
One death occurred in the bronchiectasis group, while 60 deaths occurred in the non-bronchiectasis group.
No significant difference in overall survival was observed between the two groups.

Cite This Study

Sposito et al. (2026) studied this question.

synapsesocial.com/papers/69be35166e48c4981c673330 https://doi.org/10.1016/j.esmoop.2026.106495

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Implication

Retrospective cohort study finds bronchiectasis does not significantly affect survival in advanced lung cancer patients undergoing chemotherapy, suggesting further investigation is needed.

188eP Skeletal muscle, subcutaneous and intramuscular fat as prognostic biomarkers in TKI-treated fusion-positive NSCLC

Discussion

Member takes

Implication

Key Points

Cite This Study

188eP Skeletal muscle, subcutaneous and intramuscular fat as prognostic biomarkers in TKI-treated fusion-positive NSCLC

Discussion

Member takes

Implication

Key Points

Cite This Study

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