Examines how a topical anesthetic improves dilation and muscle paralysis for eye exams, suggesting better outcomes.
Preinstillation of a topical anesthetic has been reported to increase the effect of subsequently applied mydriatics. We examined the effect of instilling 1 drop of proparacaine hydrochloride (0.5%) before applying 1 drop of tropicamide (1%). The results show that preanesthesia prolongs the mydriatic and the cycloplegic effects of tropicamide in eyes with either lightly or more heavily pigmented irides.
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Mordi et al. (1986) studied this question.
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