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March 22, 2026Current Cardiology Reviews

Meta-Analysis of the Diagnostic Accuracy of SVEAT, HEART, and TIMI Scores in Predicting Major Adverse Cardiac Events

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Authors

VTViet Nghi TranWeiss Memorial HospitalHPHoang Nhat PhamUniversity of ArizonaRIRamzi IbrahimMayo Clinic in Arizona

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Implication

Meta-analysis shows SVEAT score predicts major adverse cardiac events better than HEART and TIMI scores, indicating potential clinical utility.

Key Points

  • This research aimed to evaluate the diagnostic accuracy of the SVEAT score for predicting 30-day major adverse cardiac events (MACE).
  • Conducted a systematic literature search across five databases following PRISMA guidelines.
  • Included four studies with 1,520 patients for meta-analysis.
  • Assessed predictive accuracy using the area under the receiver operating characteristic curve (AUC).
  • Evaluated heterogeneity using the I² statistic and performed indirect comparisons with the Z-test.
  • Pooled AUC for the SVEAT score was 0.92, surpassing HEART (0.86) and TIMI (0.82) scores.
  • Significant heterogeneity (I² = 90.6%) was noted across studies.
  • No statistically significant differences were found between scoring systems despite observations of higher AUC for SVEAT.

Cite This Study

Tran et al. (2026) studied this question.

synapsesocial.com/papers/69bf3924c7b3c90b18b436c2https://doi.org/10.2174/011573403x387322251203072735
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Performance of the SVEAT (Symptoms, Vascular Disease History, Electrocardiography, Age, and Troponin) score for predicting 90-day major adverse cardiac events in patients with acute chest pain2026
  2. 2Risk Stratification of Acute-Onset Chest Pain: SVEAT Score Versus HEART and TIMI Scores2023 · 8 citations
  3. 3SVEAT score outperforms HEART score in patients admitted to a chest pain observation unit2022 · 14 citations
  4. 4Comparison of SVEAT and HEART scoring in acute chest pain2025
  5. 5SVEAT vs. HEART scores for avoiding unnecessary coronary referrals in ED chest pain patients without cath labs2026