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March 24, 2026European Respiratory Journal

Respiratory and neurological outcomes in children born preterm study (RANOPs): Preterm outcomes

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Authors

MEMartin EdwardsSKSarah KotechaJLJohn Lowe

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Overview

Cross-sectional survey identifies associations between gestational age and respiratory health in children born preterm, suggesting the need for improved monitoring.

Key Points

  • To explore the relationship between gestational age at birth and childhood respiratory health outcomes in preterm infants.
  • Conducted a cross-sectional survey of surviving preterm children in Wales and matched term-control children.
  • Collected data through questionnaires based on ISAAC assessing respiratory and general health outcomes.
  • Analyzed data by gestational age groups and divided participants into younger (<5 years) and older (≥5 years) cohorts.
  • Preterm children under 5 years reported higher rates of wheezing ever (56% vs 42%) and recent wheezing (34% vs 19%).
  • Among preterm children aged 5 or older, 43% reported wheezing ever compared to 28% of term controls.
  • Both age groups showed significant use of inhaled medication, with preterm children using it more frequently than term children, indicating severity of symptoms.

Cite This Study

Edwards et al. (2014) studied this question.

synapsesocial.com/papers/69c229b2aeb5a845df0d48e6https://doi.org/10.1183/13993003/erj.44.suppl_58.p1253
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The impact of neonatal respiratory distress syndrome on subsequent preschool wheezing in very preterm infants: a multicenter cohort study2026
  2. 2Pulmonary outcome in adolescents of extreme preterm birth: a regional cohort study2004 · 27 citations
  3. 3Growth and respiratory status at 3 years of age after moderate preterm, late preterm and early term births: the Japan Environment and Children’s Study2024 · 3 citations
  4. 4Prematurity-associated lung disease: is it asthma?2024 · 1 citations
  5. 5Reduced neonatal lung function and wheezing illnesses during the first 5 years of life2011