WCN26-4200 Investigation of the Causes of Fatigue in Dialysis Patients

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Key Points

To evaluate the effects of Citralock compared to Heparin on platelet counts and complications in dialysis patients.
Compared laboratory parameters between Citralock and Heparin in 58 patients over three months.
Measured platelet counts, INR, and TPP at one, two, and three months.
Assessed the number and type of complications occurring in both groups.
Citralock showed higher platelet counts at one and three months compared to Heparin, with p-values of 0.0242 and 0.0097, respectively.
Consistently lower INR values in the Citralock group at all measurement times, with p < 0.001.
Fewer adverse events reported in the Citralock group (5) compared to Heparin (19).
No cases of catheter obstruction in the Citralock group, while Heparin experienced 6 cases.

Compares Citralock with Heparin on coagulation measures in dialysis patients, implying Citralock's safety benefits.

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Fujiwara et al. (2026) studied this question.

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