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Prospective study examines effects of 5-ASA discontinuation on biologic therapy in children, suggesting continued use for better outcomes.
5-ASA discontinuation might negatively impact the clinical course of children with UC treated with anti-TNF. Considering the good safety profile of the drug, continuing mesalamine can be suggested as a prudent approach.
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D'Arcangelo et al. (2026) studied this question.
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