What does this research mean for the field?

Cone-beam computed tomography (CBCT) cannot reliably differentiate between periapical cysts and granulomas, significantly overestimating the prevalence of cysts compared to gold-standard histopathological diagnosis. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to assess how well CBCT imaging correlates with histological findings in large periapical lesions.

March 28, 2026Indian Journal of Dental ResearchOpen Access

Radiographic and Histological Correlation of Large Periapical Lesions: A Retrospective Analysis

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Authors

SYSumit Kumar Yadav

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Overview

Retrospective analysis evaluates correlation between CBCT imaging and histology in periapical lesions, highlighting diagnostic limitations.

Key Points

This research aims to assess how well CBCT imaging correlates with histological findings in large periapical lesions.
Conducted as a retrospective study on 94 patients with periapical radiolucencies
Examined both CBCT imaging and histopathological evaluations
Documented lesion type, location, and distribution
Performed statistical analysis to determine correlation between diagnoses
CBCT classified all lesions as cystic; histopathology confirmed only 39 as radicular cysts
49 lesions were identified as periapical granulomas
Notable discrepancy observed between radiographic and histological diagnoses (p < 0.05)
Majority of lesions located in the maxilla (84%) and anterior region (95.7%)

Cite This Study

Sumit Kumar Yadav (2026) studied this question.

synapsesocial.com/papers/69c772818bbfbc51511e2fe9 https://doi.org/10.4103/ijdr_202637s1_abs_183

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March 28, 2026Indian Journal of Dental ResearchOpen Access

Radiographic and Histological Correlation of Large Periapical Lesions: A Retrospective Analysis

View Full Paper

Ask AI

Bookmark

Authors

SYSumit Kumar Yadav

Discussion

Member takes

Overview

Retrospective analysis evaluates correlation between CBCT imaging and histology in periapical lesions, highlighting diagnostic limitations.

Key Points

This research aims to assess how well CBCT imaging correlates with histological findings in large periapical lesions.
Conducted as a retrospective study on 94 patients with periapical radiolucencies
Examined both CBCT imaging and histopathological evaluations
Documented lesion type, location, and distribution
Performed statistical analysis to determine correlation between diagnoses
CBCT classified all lesions as cystic; histopathology confirmed only 39 as radicular cysts
49 lesions were identified as periapical granulomas
Notable discrepancy observed between radiographic and histological diagnoses (p < 0.05)
Majority of lesions located in the maxilla (84%) and anterior region (95.7%)

Cite This Study

Sumit Kumar Yadav (2026) studied this question.

synapsesocial.com/papers/69c772818bbfbc51511e2fe9 https://doi.org/10.4103/ijdr_202637s1_abs_183

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