Key result
Long-standing untreated acromegaly linked to dilated cardiomyopathy and HFrEF in <3% of patients.
Why the study?
Heart failure with a reduced ejection fraction is rare in acromegaly, occurring in fewer than 3% of patients.
Highlights a rare complication of untreated acromegaly presenting as heart failure with reduced ejection fraction.
Supports screening for acromegaly in idiopathic HFrEF; extends known cardiovascular manifestations of acromegaly.
Several complications have been linked to acromegaly. However, heart failure with a reduced ejection fraction is rare and occurs in fewer than 3% of patients. We report a case of heart failure with a reduced ejection fraction due to dilated cardiomyopathy secondary to acromegaly.
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Bueno et al. (2026) studied this question. Long-standing untreated acromegaly can result in dilated cardiomyopathy and heart failure with reduced ejection fraction, a rare complication affecting fewer than 3% of patients.
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