What does this research mean for the field?

Apical right ventricular lead positioning is significantly associated with an increased risk of lead perforation. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to explore the association between apical lead positioning and the risk of lead perforation in the right ventricle.

March 29, 2026Pacing and Clinical Electrophysiology0 citations

Apical Lead Position Increases the Risk of Right Ventricular Lead Perforation: A Retrospective Cohort Study

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YMYuji ManabeYokohama Rosai Hospital TKTabito KinoUniversity of Tsukuba SAShunichi AsanoYokohama Rosai Hospital

Key Result

Apical right ventricular lead positioning was significantly associated with an increased risk of lead perforation.

Key Points

The aim is to explore the association between apical lead positioning and the risk of lead perforation in the right ventricle.
Retrospective cohort design
Analysis of lead perforation events
Assessment of lead tip positioning during implantation
Apical RV lead positioning significantly increased the risk of lead perforation.
Lead perforation incidents were uncommon but required prompt diagnosis and management.
Individualized management strategies led to favorable outcomes despite the risks.

Structured PICO

Does apical RV lead positioning increase the risk of right ventricular lead perforation?

Population

Patients undergoing right ventricular lead implantation

Intervention

Apical RV lead positioning

Outcome

Right ventricular lead perforationsafety

Apical positioning of right ventricular leads may increase the risk of lead perforation, suggesting careful attention to lead tip location during implantation is warranted.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Apical RV lead positioning was significantly associated with an increased risk of lead perforation. Although perforation was uncommon, prompt diagnosis and individualized management ensured favorable outcomes. Careful attention to lead tip location during implantation may help mitigate this risk. Given the small number of events, this finding should be interpreted as hypothesis-generating.

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Cite This Study

Manabe et al. (Fri,) reported a other. Apical right ventricular lead positioning was significantly associated with an increased risk of lead perforation.

synapsesocial.com/papers/69c8c371de0f0f753b39e404 https://doi.org/https://doi.org/10.1111/pace.70231

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