Key result
Prognostic model combining intertwined phlegm and blood stasis TCM syndrome with lipids reliably predicts MACEs.
Why the study?
The distribution of traditional Chinese medicine syndromes in post-PCI ASCVD patients, and its association with blood lipid profiles and clinical prognosis, remains unclear.
Does intertwined phlegm and blood stasis TCM syndrome associate with atherogenic lipid profiles and predict MACEs in post-PCI ASCVD patients?
Population
586 post-PCI ASCVD patients
Comparison
Intertwined phlegm and blood stasis syndrome vs other TCM syndromes combined
Design
Prospective cohort study
Follow-up
One-year
Authors
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May support TCM syndrome assessment for post-PCI MACE risk stratification; extends lipid-based models but remains hypothesis-generating pending validation.
Cohort (n=586)
No
Does intertwined phlegm and blood stasis TCM syndrome associate with atherogenic lipid profiles and predict MACEs in post-PCI ASCVD patients?
Effect estimate: adjusted OR 1.413 (95% CI 0.517 - 3.864)
p-value: p=0.501
The intertwined phlegm and blood stasis TCM syndrome is associated with an atherogenic lipid profile and, when combined with conventional lipid parameters, shows good discriminatory ability for predicting MACEs in post-PCI ASCVD patients.
Huangyu et al. (2026) conducted a cohort in Atherosclerotic cardiovascular disease (ASCVD) following percutaneous coronary intervention (PCI) (n=586). Intertwined phlegm and blood stasis TCM syndrome vs. Other TCM syndromes combined was evaluated on Major adverse cardiovascular events (MACEs) (adjusted OR 1.413, 95% CI 0.517 - 3.864, p=0.501). A prognostic model incorporating intertwined phlegm and blood stasis TCM syndrome and lipid parameters showed good discriminatory ability for predicting MACEs (AUC 0.865; 95% CI 0.816-0.914).
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