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April 1, 2026Journal of Indian Academy of Oral Medicine and RadiologyOpen Access

Comparative Evaluation of Salivary MDH and LDH between Different Types of Tobacco Users – A Cross-Sectional Study

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Authors

AAA. ArunmozhiBKB. Senthil KumarSLSuman Jhansi Lakshmi

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Overview

Cross-sectional study compares salivary biomarkers between tobacco users, indicating oxidative stress levels.

Key Points

  • The aim is to compare salivary MDA and LDH levels among various types of tobacco users.
  • Cross-sectional design involving 140 participants aged 20–45 years.
  • Participants divided into five groups: active smokers, passive smokers, smokeless users, quitters, and controls.
  • Salivary levels of MDA and LDH were measured and analyzed using one-way ANOVA and Bonferroni testing.
  • Active smokers and smokeless users had over twofold increase in MDA and 100% increase in LDH compared to controls.
  • Passive smokers and quitters had intermediate biomarker levels, suggesting partial recovery after cessation.

Cite This Study

Arunmozhi et al. (2026) studied this question.

synapsesocial.com/papers/69ccb5f716edfba7beb87b78https://doi.org/10.4103/jiaomr.jiaomr_270_25
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Also Consider

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  1. 1Determination of Malondialdehyde (MDA) Levels In The Saliva of Man Smokers Age 45 - 59 Years2025
  2. 2Salivary Malondialdehyde as a Marker of Oxidative Stress in Tobacco Chewers, with and without Oral Submucous Fibrosis: A Comparative, Cross-Sectional Biochemical Study2026
  3. 3Estimation of Salivary Malondialdehyde Levels in People with Adverse Oral Habits2024
  4. 4The Role of Salivary Biomarkers in Early Detection of Oral Precancerous Lesions2025
  5. 5Salivary Oxidative Stress Biomarkers as Predictors of Oral Health Risk Among Coffee-Drinking Smokers and Non-Smokers: Implications for Preventive Dentistry.2026