Why the study?
The extent of cardiac damage in aortic stenosis is linked to worse outcomes, but its incidence, temporal changes, and clinical impact after TAVI required evaluation.
Does preprocedural echocardiographic staging of cardiac damage predict 1-year mortality in patients with severe symptomatic aortic stenosis undergoing TAVI?
Population
596 patients with severe symptomatic native AS undergoing TAVI with baseline cardiac damage assessed
Comparison
Cardiac damage stages 0 to 4 assessed by preprocedural TTE
Design
Post-hoc sub-analysis of a multicentre randomized trial
Follow-up
1 year
Key result
Preprocedural echocardiographic staging of cardiac damage in patients undergoing TAVI stratified one-year mortality, increasing progressively from 0% in stage 0 to 21.2% in stage 4.
Authors
Loading...
Facilitates pre-TAVI risk counseling and surveillance; extends cardiac damage staging validation to baseline assessment.
Does preprocedural echocardiographic staging of cardiac damage predict 1-year mortality in patients with severe symptomatic aortic stenosis undergoing TAVI?
Preprocedural echocardiographic staging of cardiac damage strongly stratifies 1-year mortality risk in patients undergoing TAVI for severe aortic stenosis, with stage 4 damage associated with over 20% mortality.
Onuma et al. (2026) studied this question. Preprocedural echocardiographic staging of cardiac damage in patients undergoing TAVI stratified one-year mortality, increasing progressively from 0% in stage 0 to 21.2% in stage 4.