What question did this study set out to answer?

To determine whether obesity is associated with white-coat hypertension (WHT) and sustained hypertension (SHT) in young adults.

April 1, 2026Open Access

Association of Obesity With Prevalence of Whitecoat-and Sustained Hypertension in Young Adults

Q: What are the key findings of this study?

Obesity (BMI ≥ 30) was significantly associated with a higher prevalence of both white-coat hypertension (p<0.05) and sustained hypertension (p<0.01) compared to normal weight in university students.

Q: What is the clinical evidence from this study?

Study design: Observational. Population: White-coat hypertension and sustained hypertension (n=95). Intervention: Obesity (BMI ≥ 30) vs. Normal weight (18.5 ≤ BMI < 25) and overweight (25 ≤ BMI < 30). Primary outcome: Association of obesity with white-coat hypertension and sustained hypertension (p=<0.05).

Q: What does this research mean for the field?

Obesity is significantly associated with an increased prevalence of both white-coat hypertension and sustained hypertension in young adults. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Key result

Obesity linked to higher white-coat and sustained hypertension rates versus normal weight in university students.

P<0.05
n=95

Why the study?

The study was conducted to determine whether obesity is associated with white-coat hypertension and sustained hypertension in young adults.

Does obesity increase the prevalence of white-coat and sustained hypertension in young adults?

Population

University students with blood pressure ≥ 140/90 mmHg (n=95) and normotensive subjects

Comparison

White-coat hypertension and sustained hypertension vs normotensive subjects across BMI categories

Design

Observational study

Authors

MKMasao KOBAYASHIHiroshima University WSWakana SatoVascular / Pulmonary Vascular HTHaruwo TashiroAkita University

Discussion

Member takes

Implication

Supports early weight management in young adults; extends prior evidence linking obesity to white-coat and sustained hypertension.**[[1]](https://pubmed.ncbi.nlm.nih.gov/29302991/)[[2]](https://www.ahajournals.org/doi/10.1161/hypertensionaha.118.

Key Points

To determine whether obesity is associated with white-coat hypertension (WHT) and sustained hypertension (SHT) in young adults.
Retrospectively analyzed university students undergoing annual health exams between 2005 and 2014, evaluating 588 normotensive (NT) controls and 95 students with initial blood pressure (BP) readings ≥ 140/90 mmHg who completed home BP monitoring.
Categorized subjects into normotensive (NT, n=588), white-coat hypertension (WHT, n=58), and sustained hypertension (SHT, n=37) based on clinic post-exam and at-home BP readings.
Mean BMI was higher in both the WHT group (26.5±5.3 kg/m2, p<0.05) and SHT group (30.7±7.0 kg/m2, p<0.01) compared with the NT group (24.8±4.4 kg/m2), and mean BMI was higher in SHT than WHT (p<0.01).
The ratio of WHT to NT subjects in the obese group (BMI ≥ 30) was significantly higher than in the normal weight group (18.5 ≤ BMI < 25) (p<0.05).
The ratio of SHT to NT subjects in the obese group was significantly higher than in the normal weight and overweight groups (25 ≤ BMI < 30) (each, p<0.01).

Study Design

Type

Observational (n=95)

Structured PICO

Does obesity increase the prevalence of white-coat and sustained hypertension in young adults?

Population

683 university students (588 normotensive, 58 white-coat hypertension, 37 sustained hypertension) retrospectively enrolled from 44,238 students who underwent an annual health exam at Akita University between 2005 and 2014, with exam BP ≥ 140/90 mmHg and subsequent post-exam and home BP monitoring.

Intervention

Obesity (BMI ≥ 30 kg/m2) and overweight (25 ≤ BMI < 30 kg/m2)

Comparator

Normal weight (18.5 ≤ BMI < 25 kg/m2) and normotensive subjects

Outcome

Prevalence of white-coat hypertension (WHT) and sustained hypertension (SHT) across BMI categoriessurrogate

Main Result

p-value: p=<0.05

Obesity is significantly associated with a higher prevalence of both white-coat and sustained hypertension in young adults, emphasizing the importance of weight management early in life.

Limitations

Retrospective study with potential unknown selection biases
Post-exam BP measurements were obtained in only 72% of subjects with exam BP hypertension
Small number of subjects with WHT and SHT
Small number of female subjects with WHT and SHT limits extrapolation to young adult females

Cite This Study

KOBAYASHI et al. (2020) conducted an observational in White-coat hypertension and sustained hypertension (n=95). Obesity (BMI ≥ 30) vs. Normal weight (18.5 ≤ BMI < 25) and overweight (25 ≤ BMI < 30) was evaluated on Association of obesity with white-coat hypertension and sustained hypertension (p=<0.05). Obesity (BMI ≥ 30) was significantly associated with a higher prevalence of both white-coat hypertension (p<0.05) and sustained hypertension (p<0.01) compared to normal weight in university students.

synapsesocial.com/papers/69cd7e935652765b073a97f4 https://doi.org/10.20569/00005120

Topics

Hypertension management

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Association of Obesity With Prevalence of Whitecoat-and Sustained Hypertension in Young Adults

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Topics

Association of Obesity With Prevalence of Whitecoat-and Sustained Hypertension in Young Adults

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Also Consider

Topics

Also Consider