Key result
Worsening diastolic dysfunction is linked to heart failure symptoms in hypertensive heart disease.
Why the study?
The role of diastolic dysfunction progression in the development of heart failure symptoms in persons with hypertensive heart disease was not well understood.
Population
Persons with heart failure and preserved ejection fraction from Olmsted County, Minnesota
Design
Cross-sectional study
Authors
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Hypothesis-generating for diastolic dysfunction progression driving HF symptoms in hypertensive heart disease; prospective studies required before practice implications.
Cross-sectional observations suggest that progressing diastolic dysfunction drives heart failure symptoms in patients with hypertensive heart disease and HFpEF.
Lam et al. (2007) studied this question. Progression of diastolic dysfunction plays a key role in the development of heart failure symptoms in persons with hypertensive heart disease.
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