What question did this study set out to answer?

To compare the efficacy and complications of transthoracic ultrasound-guided pleural biopsy and medical thoracoscopic pleural biopsy in diagnosing undiagnosed exudative pleural effusions.

April 4, 2026Open Access

Comparative efficacy and complications of Transthoracic Ultrasound guided Pleural biopsy versus Medical thoracoscopic Pleural biopsy in Undiagnosed Exudative Pleural Effusion: Experience from a Tertiary Care Institute of Eastern India

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To compare the efficacy and complications of transthoracic ultrasound-guided pleural biopsy and medical thoracoscopic pleural biopsy in diagnosing undiagnosed exudative pleural effusions.
Prospective observational comparative study
Included 110 patients with undiagnosed exudative pleural effusion
Patients randomly assigned to undergo either ultrasound-guided or thoracoscopic pleural biopsy
Specimens analyzed via histopathological examination and GeneXpert for Mycobacterium tuberculosis
Conclusive diagnosis achieved in 96% of thoracoscopic biopsies and 95% of ultrasound-guided biopsies
Malignancy was more common in thoracoscopic biopsies (56%) while tuberculosis was prevalent in ultrasound-guided biopsies (47%)
CBNAAT positive for tuberculosis in 18 ultrasound-guided and 12 thoracoscopic cases, with two rifampicin-resistant cases in each
Longer mean hospital stay for thoracoscopic biopsies (11.3 days) compared to ultrasound-guided (1.5 days)
Fewer complications associated with ultrasound-guided pleural biopsy

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Implication

This observational study compares ultrasound-guided and thoracoscopic pleural biopsies to determine diagnostic efficacy and complications for undiagnosed effusions.

Cite This Study

Ejazi et al. (2025) studied this question.

synapsesocial.com/papers/69d0afb4659487ece0fa5ad0 https://doi.org/10.71480/nmj.v66i5.1087

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Implication

This observational study compares ultrasound-guided and thoracoscopic pleural biopsies to determine diagnostic efficacy and complications for undiagnosed effusions.

Comparative efficacy and complications of Transthoracic Ultrasound guided Pleural biopsy versus Medical thoracoscopic Pleural biopsy in Undiagnosed Exudative Pleural Effusion: Experience from a Tertiary Care Institute of Eastern India

Key Points

Discussion

Implication

Cite This Study

Comparative efficacy and complications of Transthoracic Ultrasound guided Pleural biopsy versus Medical thoracoscopic Pleural biopsy in Undiagnosed Exudative Pleural Effusion: Experience from a Tertiary Care Institute of Eastern India

Key Points

Discussion

Implication

Cite This Study