What question did this study set out to answer?

This research analyzes trends in second primary malignancies (SPM) among long-term survivors of multiple myeloma across different treatment eras.

April 5, 2026HematologyOpen Access

Temporal trends in second primary malignancies among long-term survivors of multiple myeloma across treatment eras: a population-based analysis of the SEER database

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Authors

LLLiling LuZhangzhou Municipal Hospital of Fujian Province SLShenglan LinZhangzhou Municipal Hospital of Fujian Province YCYating ChenZhangzhou Municipal Hospital of Fujian Province

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Implication

Population-based analysis highlights declining second primary malignancies in long-term multiple myeloma survivors, suggesting improved treatment safety.

Key Points

This research analyzes trends in second primary malignancies (SPM) among long-term survivors of multiple myeloma across different treatment eras.
Used SEER database for population-based analysis
Examined treatment eras ranging from alkylating agents to targeted therapies
Analyzed trends in SPM rates over time
SPM rates decreased progressively from Era 1 to Era 3
Early indications of further decline noted in Era 4
Transition to targeted therapies linked to reduced SPM occurrence

Cite This Study

Lu et al. (2026) studied this question.

synapsesocial.com/papers/69d1fde4a79560c99a0a4436 https://doi.org/10.1080/16078454.2026.2653404

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Implication

Population-based analysis highlights declining second primary malignancies in long-term multiple myeloma survivors, suggesting improved treatment safety.

Temporal trends in second primary malignancies among long-term survivors of multiple myeloma across treatment eras: a population-based analysis of the SEER database

Discussion

Member takes

Implication

Key Points

Cite This Study

Temporal trends in second primary malignancies among long-term survivors of multiple myeloma across treatment eras: a population-based analysis of the SEER database

Discussion

Member takes

Implication

Key Points

Cite This Study

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