What question did this study set out to answer?

This research aims to highlight the symptoms and challenges in diagnosing intravascular large B-cell lymphoma, particularly when presenting as neurological issues.

April 5, 2026Clinical Case Reports0 citationsOpen Access

Intravascular Large B‐Cell Lymphoma Presenting With Urinary and Fecal Incontinence: A Case Report

YHYu HeChinese Academy of Medical Sciences & Peking Union Medical College LBLiang BaiWeihai Municipal Hospital YJYuyang JiaoState Grid Corporation of China (China)

Key Points

This research aims to highlight the symptoms and challenges in diagnosing intravascular large B-cell lymphoma, particularly when presenting as neurological issues.
Case report of a patient exhibiting urinary and fecal incontinence due to IVLBCL.
Evaluation included imaging studies to identify lesions and measure interleukin-10 levels.
Multidisciplinary assessment involved multiple specialties for comprehensive management.
The patient presented with urinary and fecal incontinence associated with elevated interleukin-10 levels.
Imaging studies did not reveal specific lesions, complicating the diagnosis.
Early biopsy led to a timely diagnosis of IVLBCL, allowing for prompt treatment.

Abstract

ABSTRACT Intravascular large B‐cell lymphoma (IVLBCL) can present with neurological symptoms such as urinary and fecal incontinence. A failure to recognize this association may delay the diagnosis, especially as imaging does not always reveal lesions. Clinicians must maintain a high index of suspicion for IVLBCL in patients with unexplained neurological symptoms, persistent fever, and elevated interleukin‐10, even when imaging is non‐specific. Early biopsy and multidisciplinary evaluation are essential for timely diagnosis and management.

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