October 28, 2024Journal of the American College of Cardiology61 citationsOpen Access
View Full PaperTricuspid Transcatheter Edge-to-Edge Repair for Severe Tricuspid Regurgitation
Structured PICO
Does Tricuspid Transcatheter Edge-to-Edge Repair (T-TEER) improve outcomes in patients with severe tricuspid regurgitation?
P
Population
Patients with severe tricuspid regurgitation (full randomized cohort of the TRILUMINATE Pivotal trial)
I
Intervention
Tricuspid Transcatheter Edge-to-Edge Repair (T-TEER) using TriClip
O
Outcome
Tricuspid regurgitation (TR) reduction, 6-minute walk distance, health status, and rates of all-cause mortality or tricuspid valve surgery and heart failure hospitalization (HFH) through 1 yearcomposite
T-TEER safely reduces severe tricuspid regurgitation and improves functional capacity and health status, though it does not reduce 1-year mortality or heart failure hospitalizations.
Abstract
TriClip was safe and effective in the full randomized cohort of TRILUMINATE Pivotal with significant TR reduction and improvements in 6-minute walk distance and health status. Rates of all-cause mortality or tricuspid valve surgery and HFH through 1 year were not reduced by T-TEER.
Expert Takes1 quote
“While neither trial demonstrated a mortality benefit, these two trials showed that both T-TEER and TTVR were associated with a reduction in TR, reduction of symptoms and improvement in quality of life compared to medical therapy alone.”
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