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April 1, 2026HLA

The Novel HLA‐C*14:165 Allele, Identified by Sanger Dideoxy Nucleotide Sequencing in a Chinese Individual

Miao‐miao Liu Pei‐pei Ding Li Zhou Lin‐xia Li L H Xu

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Key Points

This research aims to identify and characterize the HLA-C*14:165 allele based on genetic sequencing.
Performed Sanger dideoxy nucleotide sequencing
Analyzed nucleotide sequences comparing HLA alleles
Identified HLA-C*14:165 differing from HLA-C*14:02:01:01 by a single nucleotide change
Documented a non-synonymous change in exon 4

Implication

Observational findings identify a new allele in a Chinese individual, suggesting genetic diversity in HLA genes.

Abstract

The HLA‐C*14:165 allele differs from HLA‐C*14:02:01:01 by a single non‐synonymous nucleotide change in exon 4.

Discussion

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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69d49f6bb33cc4c35a227d5f https://doi.org/10.1111/tan.70686

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