Why the study?
Does lower body negative pressure alter cortical activation associated with autonomic cardiovascular regulation in healthy males?
Population
8 healthy male volunteer subjects
Comparison
Lower body negative pressure at 5, 15, and 35 mmHg vs Baseline (rest) and 5-mmHg LBNP
Authors
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No immediate clinical application; extends cortical mapping of baroreflex control but remains hypothesis-generating.
Does lower body negative pressure alter cortical activation associated with autonomic cardiovascular regulation in healthy males?
This study identifies the specific cortical network, including the insula, anterior cingulate cortex, and amygdala, involved in baroreflex-mediated autonomic cardiovascular function in conscious humans.
Kimmerly et al. (2005) studied this question.
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