Key result
A single bout of dynamic exercise altered forebrain BOLD activity and elicited greater increases in heart rate and muscle sympathetic nerve activity during 35 mmHg LBNP vs no exercise (P<0.05).
Why the study?
Does a single bout of dynamic exercise alter forebrain neural activity and physiological responses during lower body negative pressure in humans?
Does a single bout of dynamic exercise alter forebrain neural activity and physiological responses during lower body negative pressure in humans?
p-value: p=<0.005
Discrete forebrain regions show differential activity patterns that may mediate altered sympathetic and cardiovascular responses to baroreceptor unloading after exercise.
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Hypothesis-generating for post-exercise baroreflex modulation; leaves open clinical relevance of forebrain activity changes.
Kimmerly et al. (2007) studied this question. Single bout of dynamic exercise vs. Nonexercised condition was evaluated on Changes in forebrain BOLD activity, heart rate, stroke volume, and muscle sympathetic nerve activity during lower body negative pressure (p=<0.005). A single bout of dynamic exercise altered forebrain BOLD activity and elicited greater increases in heart rate and muscle sympathetic nerve activity during 35 mmHg LBNP vs no exercise (P<0.05).
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