Why the study?
Does exercise improve angiogenesis, LV remodelling, and contractility reserve in a rat model of severe chronic HF?
Population
Rat model of severe chronic heart failure (post-ischaemic failing rat heart)
Design
Preclinical
Authors
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Hypothesis-generating in rat HF; extends preclinical angiogenesis data but leaves open human translation.
Does exercise improve angiogenesis, LV remodelling, and contractility reserve in a rat model of severe chronic HF?
Exercise improves angiogenesis, LV remodeling, and contractility in a preclinical rat model of severe chronic heart failure.
Leosco et al. (2007) studied this question.
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