Why the study?
Does achieving an SBP of 130 mmHg or less reduce cardiovascular risk or mortality compared to an SBP of 131 to 141 mmHg in hypertensive patients?
Does achieving an SBP of 130 mmHg or less reduce cardiovascular risk or mortality compared to an SBP of 131 to 141 mmHg in hypertensive patients?
Achieving a lower SBP (≤130 mmHg) in hypertensive patients may be associated with increased mortality compared to moderate control (131-141 mmHg), highlighting the need for randomized trials on aggressive targets.
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May warrant caution against SBP ≤130 mmHg targets in hypertension; leaves open optimal goals pending randomized trials.
Okin et al. (2012) studied this question.
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