Why the study?
Does increased cumulative ventricular pacing increase the risk of heart failure hospitalization and atrial fibrillation in patients with sinus node dysfunction and normal baseline QRS duration?
Does increased cumulative ventricular pacing increase the risk of heart failure hospitalization and atrial fibrillation in patients with sinus node dysfunction and normal baseline QRS duration?
High cumulative ventricular pacing increases the risk of heart failure hospitalization and atrial fibrillation in patients with sinus node dysfunction and normal baseline QRS duration, regardless of AV synchrony preservation.
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Minimize ventricular pacing in sinus node dysfunction to reduce heart failure risk; confirms dyssynchrony harms regardless of AV synchrony.
Sweeney et al. (2003) studied this question.
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