Why the study?
To determine whether serum C-reactive protein levels in patients undergoing colorectal surgery can exclude anastomotic leakage and allow safe early discharge.
Can serum CRP levels be used to exclude anastomotic leakage in patients who have undergone colorectal surgery?
Population
90 patients who underwent colorectal surgery with primary anastomosis
Comparison
Patients with anastomotic leakage vs those without leakage
Design
Retrospective study
Authors
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May support POD4 CRP-guided early discharge after colorectal surgery; prospective validation needed before practice change.
Can serum CRP levels be used to exclude anastomotic leakage in patients who have undergone colorectal surgery?
Serum CRP levels <180 mg/L on postoperative day 4 have a high negative predictive value for excluding anastomotic leakage after colorectal surgery, potentially allowing safe early discharge.
Messias et al. (2020) studied this question.
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